Clinically Proven

CholestOff contains an all-natural drug free blend of plant sterols and stanols, called Reducol™. Reducol has been clinically studied and proven to prevent the absorption of dietary sources of cholesterol to help lower levels of both total and LDL ("bad") cholesterol. Over 100 clinical studies have demonstrated the effectiveness of sterols and stanols (also called phytonutrients) for lowering cholesterol levels when taken in conjunction with a healthy diet and exercise plan.

CholestOff is a safe and effective for promoting healthy cholesterol levels and may be a great alternative to prescription drugs for individuals with mild to moderately elevated levels. While CholestOff may be safely combined with medication designed to lower high cholesterol, patients on such prescription regimens are encouraged to talk to their health care professional before adding CholestOff.

CholestOff provides the extra 1.8 grams of plant sterols and stanols daily that many Americans need to reach National Institutes of Health (NIH) Therapeutic Lifestyle Changes (TLC) Guidelines. These guidelines include 2 grams of plant sterols and stanols per day. The average Western (American) diet only provides 0.2 grams per day, which is only 10% of the sterols and stanols suggested by the NIH to reduce cholesterol.

†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Suggested Use:
Take two caplets two times daily with a glass of water or other beverage before meals. For optimal effectiveness, take this product between 15 and 30 minutes before eating a .

Supplement Facts:
Serving Size: 2 Caplets
Servings Per Container - 120
Amount Per Serving - % Daily Value
Sodium 15 mg - Less than 1%, Plant sterols/stanols 900 mg - *.

*Daily Value not established.

Ingredients:
Plant Sterols/Stanols (Pine Tree), Tribasic Calcium Phosphate, Calcium Carbonate, Croscarmellose Sodium, Hydroxypropyl Methylcellulose, Silica, Silicon Dioxide, Magnesium Stearate, Titanium Dioxide (artificial color), Polyethylene Glycol, Triethyl Citrate Polysorbate 80, Sodium Citrate.

No Artificial Flavors. No Preservatives. No Yeast, Starch or Gluten.

Caution:
Not for use by pregnant or lactating women, or young children. Check with your physician before beginning use of CholestOff if you are currently using medications to lower your cholesterol.

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

**The average reduction in LDL cholesterol in seven clinical studies of 3 weeks or longer supporting Reducol™ was 1.4%-24.4%. Changes in diet alone resulted in 8.9% reduction in LDL.

From Wikipedia, the free encyclopedia

Uses

As a food additive

As a food ingredient or additive, phytosterols have cholesterol-lowering properties (reducing cholesterol absorption in intestines).^[4]

Dispute

The status of the safety and efficacy of the use of phytosterols as a food-additive is disputed. While recent studies suggest that dietary supplementation of plant sterols can have a leveling effect on human cholesterol, some studies would appear to indicate that they are hard on the heart, arteries and blood-vessels, meaning, depending on intake, they may do more damage to the circulatory system than they alleviate.^[5]

Potential benefits

The FDA has approved the following claim for phytosterols: "Foods containing at least 0.4 gram per serving of plant sterols, eaten twice a day with meals for a daily total intake of at least 0.8 gram, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease."*

Sterols can reduce cholesterol in human subjects by 10% to 15%.^[6]

The mechanism behind phytosterols and the lowering of cholesterol occurs as follows: The incorporation of cholesterol into micelles in the gastrointestinal tract is inhibited, decreasing the overall amount of cholesterol absorbed (see cholesterol absorption inhibitor). This may, in turn, help to control body total cholesterol levels, as well as modify HDL, LDL, and TAG levels. Many margarines, butters, breakfast cereals, and spreads are now enriched with phytosterols and marketed toward people wishing to lower their cholesterol levels.

Researchers in Uruguay who conducted a small case cohort study suggested an association between dietary sterol intake and decreased risk for the development of gastrointestinal cancers;^[7] however, a subsequent large-scale study from the Netherlands reported that high dietary intake of plant sterols was not associated with a lower risk of colon and rectal cancers.^[8]

Potential risks

There is some evidence that phytosterols can promote atherosclerosis in susceptible individuals having a rare genetic condition called sitosterolemia.^[9][10] A 2008 study conducted in Finland showed that sterols can accumulate in heart valves, suggesting that dietary sterols might increase the risk of aortic valve stenosis.^[11]